Aside from probably every game ever made by KEY, I'd say some of my favorites are:
To Heart
Mizuiro
D.C.~Da Capo~
Kana~Imouto~
Kazoku Keikaku
Comic Party
Inagawa de Ikou!
Wind-a Breath of Heart-
Kimi Ga Nozomu Eien
MuvLuv
Phatom~Phantom of Inferno~
... and the list goes on ...
A some of my older favorites would be:
Custom Mate 3
Lovers
True Love
VR Date - May Club Gogatsu Kuchibi
Abunai Bunkasai
Ningyo -Rako-
Only You
Three Sister Story
Nocturnal Illusion
DiviDead
Ah, the glory days of the PC-98XX system... how I miss them. >.>;
With the remake of Lovers out I'll probably have something to do for a while.