I feel sad for Alicia and Beth. The spore awakened beth against her will, and then to see her futily attack Priscilla was horrible. It got even worse when Alicia awakened as well ,essentually giving up her humanity to try and save her sister. All for nothing.
They did have feelings after all.
Say what you want about Yagi, but he has a nack for makeing you care, or at least be intersted in a character that you know very little about. Other examples bieng Flora, Undine, and possibly even Jean. They weren't in there very long but all there deaths mattered.