I tried going through BOSS but not TFS EDIT. I am not very familiar with Mod editing, although Mods I use are usually 5 star and above with thousands of endorsements. Cept...when I disable them through NMM it was anything but clean
Judging by the Paypus log, there were a lot of things causing glitches even though they were disabled years ago (some mods are pre-NMM so they can't be cleaned out, little bit of file here and there), stuff like light potion mod, some odd ball adult mod I installed/unintalled in like two hours after, a bunch of companions I uninstalled after finding out they are nothing more than a pretty face---or really awful quest.
So I decide to go through the clean-wipe, since right now my Windows is a bootlegged version and is running a 32Bit system on a 64 bit machine (finally got a legit CD). Since Skyrim was the biggest ticket I wanted to save, this give me the excuse to burn down my comp for a resurrection.