I see two options on how the current situation is going to be resolved:
1.) Either Tsukune is going to reach a new level of control over his vampire / Shinso powers, without going berserk (which, wouldn't achieve anything, except for Tsukune getting himself killed), which would actually make Issa acknowledge Tsukune's strength (since, this chapter foreshadows the fact that some sort of confrontation make occur between them).
2.) This isn't the last time some unexpected plot twists that this chapter is going to bring - something will occur that will change the situation again.
Anyway, apart from the situation with Outer Moka, I have no doubt that Tsukune and the rest are going to survive this, pretty dificult situation, the question is, how Ikeda is going to do that