Full Moon wo Sagashite - shoujo at its best
Juuni Kokuki - hooked me from the beginning and never let go
Trigun - never have I come across a more likeable main character
Haibane Renmei - awesome surreal fantasy
Hachimitsu to Clover - gave me the tingles and I found myself watching certain scenes over and over
Mushishi - the only anime ever to consistently leave me feeling awed as the ending song played