Except for what I'd call an original "prologue" before ~9:30, where chapter 1 really began, the rest was mostly faithful to the source. Oh, the joys of finally seeing one of my favorite manga, and Rea herself, animated.
While I still think Chihiro's voice is a bit too deep for him, I believe I'm going to have an easy time adjusting to his voice by virtue of Ryohei Kimura's performance here. Everyone else behaved as I expected them to.
Studio DEEN did a pretty good job for the first episode, and even gave me some Shaft vibes there. Also, I love the ED, and the OP wasn't at all that bad.