Now that I realize something important about why every girl in I.S.A., especially Personal I.S. owner is such a badass...
Think about it a little, that I.S. boosted the capability of user by reducing the strain put in their body. However, as soon as this support removed (put the I.S. at sleep mode) the pilot lose all those and greatly exhausted.
This maybe not the real case.
Human body adapts, and since what I.S. did is reducing the strain, theoretically the pilot can train themselves beyond normally. While this can cause over-exhaustion thus rather risky, those developed ALONG with their I.S. instead of forcing themselves may found that their body has developed to work more efficiently with the I.S..
Now I can justify the 'Trinity Concept' of performance measurement, YAY!