Just watched the first episode. Here are my thoughts:
The opening theme seems a bit too happy-go-lucky, but the overall timbre of the instruments they used fits very well with the background of the story. And that last long shot of Eruruw was just magnificient...
Spoiler for parts of episode 1:
It looks like they decided to shorten some of the earlier parts of the game, and took out the part where they had to fight the monkey-like animals ravaging the crops. Though, that did make the episode title a bit odd, since it was the name of the battle where you fight the monkey-like things in the game. The voice acting was decent, though I thought both Eruruw and our main hero have voices that are a bit too low pitched. Aruruw's voice seems to be nicely done, as well as grandma's voice. The entire art gave off that nostalgic, old-ish anime feel, which was pretty nice, although I wished they could've made the opening animation a bit more fluid and some of the keyframe animation could've be better.
Nuwangi's character is developed rather nicely. The anime portrayal brings out (what's left of) his humanity and makes him a lot easier to feel sorry for. It's a pity they moved the tail-grabbing scene to after the main hero starts walking around again, and a pity that they removed the cute little sound effects Aruruw makes when running off. It's amusing they decided to keep all the terminology from the game, so things like Owruo are kept in their original pronunciation. Hopefully, they'll put up a glossary for those who haven't played the game, as there *are* a lot of terms.
Personally, I liked the ending theme more, because of its eccentric rhythm and exotic feel. Also, that ending picture was really nice, and you'll know what it stands for by the time the series ends, as it is very important.
Looking forward to episode 2...