CS6 (Photoshop), the biggest new thing is the 3D feature.
http://www.digitalartsonline.co.uk/t...-new-3d-tools/
I'm not entirely sure since I haven't explored its full potential yet. I used elements 6 for a long time, then CS2, but I don't know how to do any of the new stuff with CS6, so I can't really tell you aside from the 3D. I got CS6 mostly because CS2 was a bit dated and the new CS6 was supposed to be awesome. I have never used any of the other Creative suite programs, except Bridge, which I don't really use much.