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Its a variation on this theme: if you knew someone was only going to live five more years while you had an expected lifespan of many more decades - what is the pain worth to you to be with this person? What if everyone you knew was a "mayfly"?
This problem is engaged in works like Heinlein's Lazurus Long series of the Methuselah's Children or the Hanbun no Tsuki ga Noboru Sora series set in a hospital.
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