After playing Yakuza 2 (Ryu ga Gotoku 2) and experiencing MGS4 ending, I'd have to say Yakuza 2 is better, because it came out earlier and is pretty much the same thing. (Kojima may have even copied it :P)
Its that or Metroid prime on the GC, experiencing the last boss at the time it came out was truly mind blowing. Never had I seen a game that replicated organic enemies so well. Games before that always looked crappy and their motion wasn't very fluid.
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