Personally, I think Hazumu fits the role of a female better than a male, he was very effeminate to begin with. Tomari, Yasuna, Asuta and the rest who knew him in the past however had difficulties (obviously) with his sudden gender change.
P.S: I think Hazumu was effeminate because of some crazy upbringing from his wacked parents. Remember they said, "We've always wanted a girl." right after they knew about Hazumu's transformation? Genes may play a part, but socialization is a key factor too.
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