[Rui Brennan]

Originally Posted by Mercurius

After looking at it some more:

Spoiler for Portrait:

The girl has a rose on her head and rose patterns on her stockings. Probably a connection to the damaged rose that always 'disappears' at the beginning of each game. Hell, she just might BE that rose.

Maybe... in fact...

Spoiler for Another Clue:

...the girl (both in the portrait and in-game) has a ribbon in her chest. Remember what happened with the rose? What George did?... .
Besides, (but this theory is even wilder) the conversation with Rosa can mean that she "saved" that rose and gave it to Dr. Nanjo in order to take care of it as a gift for Maria

BTW, hi everyone, long time lurker, first time poster .