Personally, I'm not too bothered by the whole Ashley-Sherry affair, but I don't like the idea of the timeline being spread too far apart (2008-2013)... Both Leon and Chris aren't getting any younger...
At the same time, I hope "
ten years from Raccoon City" isn't being too literal, there's no reason why the story can't continue pass RE5 given how every other Terror Cell in the world could easily get their hands on bioweapons.