It was Keiji Infuane's idea for a westernization, then a backlash happened to capcom not just DmC, but other titles as well.
The thing is about the original DMC is that Capcom still has the rights to it, that's why Capcom said the table is open for anything, but basing in all the interviews they just wanted to try something new on this series, they can make a sequel to the original series or DmC2 anything is possible, but to me they're just looking at the sales now, if this doesn't reach their target goal, bet you the original DMC will be back.
Also another thing is that Itsuno doesn't want anymore the original Dante and any other original DMC characters to be in to be in other games. Capcom staff, persuaded him to add Dante, Trish and Vergil to be in MVC3/UMVC3 and the cross over game ProjectZone. Other than those games you don't see any DMC characters crossing over on any other games except the ones mentioned.
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Vampire+Sisters
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