Speaking of Ghoul/Vamp Tsukune. I remember having DarkStalkers chronicles, replayed it again and saw DEE. Who is really Donovan who has a half vampire blood like Tsukune. Dee is Donovan's form that is a full vampire while having the old Donovan's moveset and his ending an unknown girl defeated her, who most likely is Anita since in DS the ending Donovan couldn't beat the vampire blood and Anita was all grown up in the ending.
Remember Tsukune life is on a thread, if the holy lock breaks we dunno if he can control or will he be overcome by the vamp blood.