It'll either be. . .
Kabuto in some ultimate betrayal sort of deal: "I'm sorry orochimaru-sama, but this time you've gone to far. . ."
Remember Orochimaru trust Kabuto completely so he would be the only one capable of getting close enough to stab orochi in the back.
Or Sasuke in some type of student overtakes the master think: "You want my body, come get it. . ."
After all sasuke's just with oro for power, and how can he test his power better than defeating a sannin. After all, he'll want to see if he's strong enough before he goes after Itachi.
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