I don't think Gilgamesh has been corrupted by the grail, at least not to an extent that would change his personality. His behavior towards Rider is merely a rare exception. He's treated everybody else like trash in this war, and clearly derived pleasure from seeing other people suffering (Saber in particular). If you discount his interactions with Rider, then F/Z's Gilgamesh is really not all that different from F/SN Gil.
The differences there are could be attributed to the fact he's spent 10 long years observing the human world, and what he's witnessed made him grow even more disgusted of humanity.
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