Phew. Time for Zero's take on this, huh? Like most of you, I'm not lazy to shorten my comments and I actually enjoy taking my time
Overall it was a great episode, and a real fun one to watch as well. It was also a good relief considering 22 got me really depressed, and as I'm recovering from it, good ol' Lucky*Star awesomeness is always good.
First, Kagamin~'s face while she used Kona-chan's computer is priceless. "Hey, wanna talk about this computer for a bit?" should also be entered as one of her most memorable lines. The junk-mail scene was also hilarious. I almost died laughing at the E-mail subjects. "You've won 5 million bales of rice!". Who hasn't ever gotten one of these?
The only joke in the entire episode I didn't get was after that, where Soujirou makes a cup-ramen and says "I got teased...". Does anyone want to shed some light on that?
I also feel kinda sad for Hiyori and Patty - Cousin Yui is all over Minami-chan and completely forgets about them. I've had that happen to me quite a few times. The arrows pointing at them also make the whole scene even funnier. But I think that the
most memorable scene from this episode is when Konata, Hiyori and Patty are discussing the whole "younger-sister-moe" complex. The three of them seem to know exactly what the others were thinking and even agreed on it. But then the "Attack of scorn from the common folk" kicks in and they all feel so rejected. I don't know a single otaku who's never felt that the others around them gave'em that "What the..." look when they made an anime-related comment. In fact, I get that quite a lot from my family.
But releasing Minami-chan's secret into the open... That's Konata for you! "I normally base my manga off of personal experience" - Yutaka's reaction was indeed, moetastic.
Kagami's phone call was also pretty interesting, although I don't know if that had much to it as you guys are thinking... And HELL no, I don't want that dude from episode 21 touching my beloved Kagamin~!
I also think that another high-point in this episode was the topic on music featuring Patty. You could say it's a "western-otaku" thing, but the fact that all of these bands - and the reason she listens to them - is because they made Anime songs applies very well to us, here in the other hemisphere. I mean, without watching Anime, would most of us ever listen to a japanese song? Perhaps not ones that we would like, at least. One of the points in this episode that I liked is that they gave us, western-otaku, a little attention through the eyes of Patty and how she thinks of Japan. The topic on Maids was actually enjoyable, since some us rarely remember that the real Japan doesn't have maids - as we know them - running around in every household like some series make us believe. "Otakus are the pride of Japanese Culture" - or so she says.
Konata playing with Kagami's pigtails was also
moetastic. Misao's "You're scary to begin with, Hiiragi!" also had me rofling.
Also, Patty's comment: "Isn't this image bugged up?" shows that she's probably just been introduced to hentai and the like, at least in a major way. I mean, a great deal of what's published in the hentai/doujin circle has to be censored by law, right? She shouldn't have been so surprised by it if she had. Poor Patty-chan, being corrupted by Konata's legacy.
And, of course, Nanako's chain of unfortunate events always shine brightly whenever they show up. That has happened to me so many times that >every< time I write something in a webpage, I copy it as a whole before sending it. It would be great if they added a scene where she actually did the same, but forgot about it and copied something over. That's the problem I'm facing at the moment.
All in all, a great, normal Lucky*Star episode. Misao's appearance are always fun and I'm getting the vibes that her seiyuu will get out of her Lucky*Star role much like Aya-chan did after voicing Haruhi. Her voice is solid and cute, and the amount of "Hiiragiii" and "Uuus" and "Waaahs" that expresses Misao's personality so well might also count a bit for that. I don't want to dwell much on what the last episode will be like, otherwise I'll expecience Post-anime-depression even before it actually ends. This is definitely a series that will be missed, but also remembered for years to come.
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Maybe someone could tell us if that's impossible or comically tedious. 
Need listerine now.
