Well the PuchiM@su Drama CDs are almost essentially an audio CD of the manga with the exception of an original episode in each one. Oh, and there is no "P". The blank is mainly filled in by either Ritsuko or by narration. There's also an OP(?) PuchiM@su song.
...and by "talk" if you mean the likes of Yayo going "
U-uu~" or Chibiki saying "
Dazo~" and the such then yes, they "talk".
Back on talking about possibe PuchiM@su merchandise, I do hope that IF they do ever make plushies then they would make the alternate version too. Y'know, Chihya with cat ears, Yukipo with a racoon(?) tail, Yayo with long hair, and Afu with the "awakened" Miki hair.
But thats only IF they make plushies...orz