1. FMP TSR
2. Ichigo Mashimaro
3. Pani Poni Dash
4. Honey & Clover

Those are the only shows that actually left a really good impression on me

The best one of 2005 has to be School Rumble and the best series for 2006 will also be School Rumble.

Other then that Yakitate Japan,Mahoraba and Mai Hime I liked.

I didn't watch much this 2005. I'm sad.

I think a great prospective this 2006, however, is Ergo Proxy. I'm still drooling ...

Top 5
 

Honey & Clover
School Rumble
Emma
ParaKiss
FMP TSR

Trinity Blood
Air
FMP TSR
Shuffle!
AMG
Shakugan no Shana
Bleach
Mai Otome
(no particular order, 'cept for Trinity Blood which is tops...)

1. Jigoku shoujo
2. Tsubasa chronicle
3. Gun X sword
4. Cluster edge
5. Mai-otome

1. Gankustuou
2. Mai Hime
3. Honey and Clover
4. Pani Poni Dash
5. Shuflle

Judgement pending on Mai Otome

And now I have my current best of 2005: Rozen Maiden: Traumend. The second season is even better than the first one!

For this year I would say :
- Honey and Clover
- Kamichu!
- Emma
- Full Metal Panic IInd
- Noein
- Glass Mask
- Snow Queen
- Rozen Maiden T
- Mushishi

For me. I'd have to say
- Black Cat
- Blood+
- Eyeshield 21
- MAJOR 2nd Season

I must say I've avoided almost everything thats come out this season (Too much Harem and I hate Harem, hell it was all Harem pretty much). Although Eureka 7 looks pretty darn good. I know for a fact Mushishi was good and Bleach was interesting when my friend showed it too me. Hopefully we can get some good Mecha, Shonen, Action, or thought provoking anime later in 2006 instead of mind-numbing high-pitched screaming idiot girls fawning over a generic male archetype. That's all I really ask for.