[serenade_beta]

Originally Posted by mikesince83

Spoiler for Episode 3:

It's possible his wife thinks he ran off with another woman since he's now missing, with an empty ring box left behind. Then again, maybe she knew about the spore.

Spoiler:

The latter.
Kouki handed her the spore in ep2. That's why she seems to have understood what happened to him (well, not the specifics though). But she definitely knows he's gone, just like her brother.