Here are two factors that I'd like to speculate:
1. Mr. 2 Bon Clay's fate- we saw that he had to stay behind and he was facing Magellan. The only chance we may have for Mr. 2 to survive is if Magellan's diarhea starts acting up again.
< (wheezing laugh)
2. What awakened zoans are- my brother thinks they're descendants of previous zoan devil fruit users but I highly doubt that. I would think that they may be animals who have eaten zoan devil fruits of that same nature.
i.e.: Minotauros- a bull or cow who had the Ushi Ushi no mi model standard
Minozebra- a zebra who had the Uma Uma no mi model zebra
Minorhinoceros- a rhino who had the Sai Sai no mi (Sai japanese for rhino)
Minokoala- a koala who had the Kuma Kuma no mi model koala (koalas could be related to bears)