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^
It most likely means that a second Ophis (called Lilith), made from the power that was stolen from the original Ophis, which happened in volume 11, is going to appear in volume 16, and also show some attraction to Ise - probably due to his chick magnet status.
Or that there is more to the Infinite Dragon, then we knew so far, and there exists some more evil version of Ophis (I'm only basing this on the name that was provided in n0m@n's spoilers) that is going to make an appearance due to Rizevim's actions.
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