Nope. Despite that GXP happens AFTER OVA3, the only advantages to having seen GXP is:
1. You've already been acquainted with Noike.
2. You know EXACTLY what kind of person Seto is, so her meddling comes off as even more comical.
3. You already know that ...
4. You already know that Airi hates being called "obachan" - Plus you already know that she is...
That's about it, really. Everything else is still new. However, if you were a well-informed Tenchi fan, you'd also already know...