Spoiler for Character Art:
The one with the vacuum is Bloody Mary the SkullGirl every body is after and the boss of the game! the one in the nurse outfit with the eyepatch is Valentine! That blob with some of the characters body parts is Double is probably be the mid-boss!
They changed Ms. fortune's Character design
And Painwheel is a Anti-SkullGirl like Peacock
At their youtube channel has their panel at EVO and the side tournament!
http://www.youtube.com/user/SkullgirlsGame