Depending on the severity of the issues that it's causing, that would be one route to be taken, and not a very fun one. It takes quite a while (typically a day or more, depending on how much things you have to reinstall) to "restore" your computer back to normal. If you have no other options left and have to take that route, I highly advice you install your firewall, anti-viruses, pop-up blockers, spyware blockers, etc. in safe mode without networking. Also periodically have them scan your computer in safe mode out of safety's sake. Just keep in mind: Utilities = Safe Mode, Everything Else = Normal.
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