Genophage isn't that bad its just that the krogan aren't used to it yet, all it does it quell their numbers to a more manageable level like birth control its just when you are used to having 8 babies then your numbers get cut down to 2 or 3 if you're lucky then it seems like such a massive blow. Especially to the krogan who need to mass reproduce to replace all the ones that get killed in action, I mean look at Wrex because of their numbers they are finding the need to unify and share instead of keeping their tribal instincts.
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