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Symantec Corporate Edition varies in price due to the amount of users. The last time I checked, the unlimited subscription is $3,000 plus. It checks and scans the client and server computers periodically, and I have yet to see a limit on the amount of computers that the software can be installed for that high of a price. The catch is if you wish to upgrade the software to the next version up, you'd need to shell out another $3,000 plus.
You can also look into Kaspersky's server-client anti-virus software. The price may be higher, but it's due to the fact that the quality of their product tends to be higher.
Ledgem is right about the fact that you should worry more about your security than anti-virus protection. The anti-virus is your defense upon the entry ONCE it bypasses the firewall. In order to ensure that not just anything gets passed the firewall unless permitted, you should look into the different types of firewall software out there for your clients and possibly server.
The server tends to be different issue when it comes to firewalls, considering the purpose the server serves. If it's running a database and sharing files, printers, etc, as well as hosting the internal website and/or the server acts as a DHCP host for the rest of the network, then it would be best to look for a firewall specifically designed for a server so you don't have to walk to the server every other second or minute to permit a local IP to connect to the server, or so on and so forth.
This isn't an easy task. Choosing carefully and wisely takes a lot of time and research.
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