Their regeneration seems to be the kind they need to actually focus on and activate, almost like a healing spell. Answer: knock them out with a strong blow to the head.
I've said all along, that I think we give far too much credence to their regeneration abilities. We've seen exactly one person regenerate, and Cypha had to place her other hand on the spot and almost cast a spell to get her arm back. If Signum had kept up the pressure, Cypha might not have had time to get the arm back.
Also, turning into a lump of flesh seems to be the result of their regeneration going haywire, so I'm also betting they are very careful about how they use it.
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