It's unclear to me who the manga is targeted to. It's in a magazine that
"subvert the preconceptions of shōnen and shōjo magazines"
http://www.animenewsnetwork.com/news...nch-next-april
However the female manga-ka is known for drawing yaoi manga. And while I am 100% sure Brave 10 is not a yaoi manga, I would be surprised if she isn't drawing her male characters to appeal to female fans. Still perhaps the manga is not meant to be shounen or shoujo (like the magazine description says).
But just looking at the seiyuu cast, the character designs, and the fact that it is a "reverse harem" to me it seems the anime
at least is being marketed to a female audience. Also in most reverse harems you can usually tell who the main couple will be right away.
Also I never thought the Bleach characters were Bishounen at all. Although Reborn is a good argument.
But really I don't care if it aimed at a male or female audience. But it seems some people on here care that it might be aimed at a female audience. Does that really make a difference in your enjoyment of the series?