Tsk, tsk ,tsk. All these gloom and doom predictions when this is not a crying game imo.
Spoiler for ending speculation:
Yorito gets his memory back. It turns out that he is a daywalking yaka. He and Takeshi combine knowledge and Aono, Mayuko and Matsuri become daywalkers. Yorito and Matsuri explain it more clearly to Aono that they are not going to abandon her. Matsuri moves in with Yorito and Aono and they all live happily ever after.
Mayuko and Takeshi move into a house that was for sale in the neighborhood.
Sae starts running after Takeshi.