Considering the mention of Schrodinger's Cat, and the numerous images of murders... I'm going to assume we're going to see 999 no Naku Koro ni, meaning lots of "closed room murders."
If that's the case, Sigma'll probably have to decide whether or not to trust people, and "game of betrayal" might refer to the fact that depending on who he trusts and what he does, there'll be different murders/killers.
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